The CERAD neuropathology criteria are widely used in the
US and abroad for studies of Alzheimer’s disease and
other dementias of the elderly. This assessment was developed
to fulfill the following aims and purposes:
- To establish accurate,
reliable, and standardized neuropathological criteria for
the diagnosis of Alzheimer’s disease (AD)
and other dementias;
- To develop a practical protocol for postmortem
examination of the brain and provide standard, reliable
measures for determining the neuropathological spectrum
of Alzheimer’s disease and other dementias;
- To extend
the CERAD assessments to include dementias associated with
other disorders such as vascular disease, Parkinson’s
disease, alcoholism, and depression;
- To establish a data base
for pooling the neuropathological findings of Alzheimer’s
disease and other dementias with clinical information on
demented and cognitively normal subjects.
The Neuropathology assessment packet includes the following
A. Demographic Data
B. Clinical History
C. Gross Examination of the Brain
D. Cerebral Vascular Disease: Gross Findings
E. Microscopic Vascular Findings
F. Major Non-vascular Microscopic Findings
G. Microscopic Evaluation of Hippocampus and Neocortex
H. Assessment of Neurohistological Findings
I. Neuropathological Diagnosis
J. Final Assessment
This assessment packet includes a detailed manual, The CERAD
Guide to the Neuropathological Assessment of Alzheimer’s
Disease and Other Dementias.
See the CERAD list of publications on neuropathological
findings in AD.
For information regarding purchase of this assessment material, check the Order Form.
Printable version of this page.